Telomere structure in mammals; T-loop and D-loop are presented together with schematic representation of the shelterin complex on telomeric DNA. The shelterin complex consists of six proteins: TRF1 and TRF2 (telomere repeat-binding factor 1 and 2), RAP1 (repressor/activator protein 1), TIN2 (TRF1-interacting nuclear factor 2), TPP1 (TINT1/PTOP/PIP1 protein) and POT1 (protection of telomeres 1).

 
 
  Part of: Achrem M, Szućko I, Kalinka A (2020) The epigenetic regulation of centromeres and telomeres in plants and animals. Comparative Cytogenetics 14(2): 265-311. https://doi.org/10.3897/CompCytogen.v14i2.51895